from pheno_utils import PhenoLoader008-serum_lipidomics
Serum lipidomics dataset
Description
High throughput untargeted lipidomics in serum by Ultra-High-Performance Liquid Chromatography Electrospray ionization High-resolution mass spectrometry (UHPLC-ESI-HRMS).
Introduction
The serum metabolome is known to represent a variety of environmental, genetic and other endogenous factors (Bar et al. 2020). Lipidomics is a subfield of metabolomics, which is defined as the study of pathways and networks of cellular lipids in biological systems. Lipids perform various functions within the body, from structural components of cell membranes, to energy reserve and regulating hormones. These pivotal functions highlight circulating lipids as playing a key role in a number of age-related diseases such as cardiovascular disease and stroke (Holmes et al. 2018; Michos et al. 2019).
Measurement protocol
The data acquisition process can be broken down into these three main stages: 1. Sample preparation and experimental design, performed by the wet lab at Weizmann 2. Operating the MS machines to obtain the raw spectral data, performed by the Weizmann service unit 3. Processing the raw spectral data to obtain the final format for research, performed by the computational lab at Weizmann
Sample preparation and experimental design
The process starts with drawing blood from the participants during their visit to the assessment center (see Sample inventory for details). Serum is extracted from the sample and is aliquoted into 5 smaller tubes. All the barcodes mapping are currently documented in the LabCollector. The team at the wet lab performs the sample preparation and samples are arranged in working plates of size 96. Every plate contains 92 samples from study participants, and 4 QC samples that will be used for systematic bias correction. The QC includes two types: 1. Empty well for blank (position 93 in the plate) 2. Anchor sample - this is a sample that was pooled from a large number of study participants, and is used as validation for the statistical correction methods. Same sample is used repeatedly. (position 94 in the plate) 3. Two NIST samples - these are standardized technical replicates that contain a predefined mixture of human serum metabolites. These samples are later used for running order and batch correction of the data. (positions 95-96 in the plate)
For every plate, the team at the wet lab produces an experimental design file that describes the layout for the analysis of the plate. Mainly, it describes the ordering of the samples to be injected into the MS machine, including the various sample types (10K, empty, NIST, anchor), the tube barcode, their quantity and location. Systematic removal of technical noise is partly performed based on this experimental design file.
Operating the MS machines to obtain the raw spectral data
The service unit in Weizmann is responsible to operate the MS machines in order to profile the samples. According to the service unit staff, initial QC checks are performed after the injection of every plate, making sure that internal standards are identifiable, and that the sensitivity of the MS machine is within reasonable limits.
Processing the raw spectral data to obtain the final format for research
Lipid annotations were obtained by comparing the mz, retention times and ccs values to equivalent empirical measurements from a library that was profiled on the same instruments with longer running times (26 minutes).
Data availability
The information is stored in 1 parquet file: serum_lipidomics.parquet
Relevant links
pl = PhenoLoader('serum_lipidomics')
plPhenoLoader for serum_lipidomics with
202 fields
2 tables: ['serum_lipidomics', 'age_sex']Data dictionary
pl.dict| folder_id | feature_set | field_string | bulk_dictionary | data_coding | completed | field_type | bulk_file_extension | relative_location | description_string | sampling_rate | stability | units | strata | sexed | array | list_of_tags | debut | transformation | pandas_dtype | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| tabular_field_name | ||||||||||||||||||||
| collection_date | 8 | serum_lipidomics | Collection date (YYYY-MM-DD) | NaN | NaN | NaN | Date | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | NaN | NaN | NaN | NaN | Single | NaN | NaN | NaN | datetime64[ns] |
| collection_timestamp | 8 | serum_lipidomics | Collection timestamp | NaN | NaN | NaN | Datetime | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | NaN | NaN | NaN | NaN | Single | NaN | NaN | NaN | datetime64[ns, Asia/Jerusalem] |
| timezone | 8 | serum_lipidomics | Timezone | NaN | NaN | NaN | Categorical (single) | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | NaN | NaN | NaN | NaN | Single | NaN | NaN | NaN | string |
| 22:6_cholesteryl_ester | 8 | serum_lipidomics | 22:6 Cholesteryl Ester | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| acca_c10:0 | 8 | serum_lipidomics | AcCa C10:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| acca_c16:0 | 8 | serum_lipidomics | AcCa C16:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| acca_c18:1 | 8 | serum_lipidomics | AcCa C18:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| cer_d18:0/c16:0 | 8 | serum_lipidomics | Cer d18:0/C16:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| cer_d18:1/c12:0 | 8 | serum_lipidomics | Cer d18:1/C12:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| cer_d18:1/c14:0 | 8 | serum_lipidomics | Cer d18:1/C14:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| cer_d18:1/c16:0 | 8 | serum_lipidomics | Cer d18:1/C16:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| cer_d18:1/c18:0 | 8 | serum_lipidomics | Cer d18:1/C18:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| cer_d18:1/c18:1 | 8 | serum_lipidomics | Cer d18:1/C18:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| cer_d18:1/c20:0 | 8 | serum_lipidomics | Cer d18:1/C20:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| cer_d18:1/c22:0 | 8 | serum_lipidomics | Cer d18:1/C22:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| cer_d18:1/c24:0 | 8 | serum_lipidomics | Cer d18:1/C24:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| cer_d18:1/c24:1 | 8 | serum_lipidomics | Cer d18:1/C24:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| cer_d18:1/c25:0 | 8 | serum_lipidomics | Cer d18:1/C25:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| cer_d18:1/c26:0 | 8 | serum_lipidomics | Cer d18:1/C26:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| coenzyme_q10 | 8 | serum_lipidomics | Coenzyme Q10 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| dag_32:1 | 8 | serum_lipidomics | DAG 32:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| dag_34:1 | 8 | serum_lipidomics | DAG 34:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| dag_34:2 | 8 | serum_lipidomics | DAG 34:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| dag_36:2 | 8 | serum_lipidomics | DAG 36:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| dag_36:3 | 8 | serum_lipidomics | DAG 36:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| dag_36:4 | 8 | serum_lipidomics | DAG 36:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| dag_36:5 | 8 | serum_lipidomics | DAG 36:5 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_12:0_lauric_acid_(dodecanoic_acid) | 8 | serum_lipidomics | FA 12:0 Lauric acid (Dodecanoic acid) | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_14:0_myristic_acid_(tetradecanoic_acid) | 8 | serum_lipidomics | FA 14:0 Myristic acid (Tetradecanoic acid) | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_17:0_margaric_acid_(heptadecanoic_acid) | 8 | serum_lipidomics | FA 17:0 Margaric acid (Heptadecanoic acid) | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_18:0_stearic_acid_(octadecanoic_acid) | 8 | serum_lipidomics | FA 18:0 Stearic acid (Octadecanoic acid) | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_18:1 | 8 | serum_lipidomics | FA 18:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_18:2 | 8 | serum_lipidomics | FA 18:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_18:3_gamma-linolenic_acid_((z)-6,9,12-octadecatrienoic_acid),_w6 | 8 | serum_lipidomics | FA 18:3 gamma-Linolenic acid ((Z)-6,9,12-Octad... | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_19:1_(z)-10-nonadecenoic_acid,_w9 | 8 | serum_lipidomics | FA 19:1 (Z)-10-Nonadecenoic acid, w9 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_20:0_eicosanoic_acid_(arachidic_acid) | 8 | serum_lipidomics | FA 20:0 Eicosanoic acid (Arachidic acid) | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_20:1 | 8 | serum_lipidomics | FA 20:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_22:0_behenic_acid | 8 | serum_lipidomics | FA 22:0 Behenic acid | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_22:1_(z)-13-_x0080__x008b_docosenoic_acid_(eruccic_acid),_w9 | 8 | serum_lipidomics | FA 22:1 (Z)-13-€‹Docosenoic acid (Eruccic acid... | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_23:0_tricosylic_acid | 8 | serum_lipidomics | FA 23:0 Tricosylic acid | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_24:0_lignoceric_acid | 8 | serum_lipidomics | FA 24:0 Lignoceric acid | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_24:1_(z)-15-tetracosenoic_acid_(nervonic_acid),_w9 | 8 | serum_lipidomics | FA 24:1 (Z)-15-Tetracosenoic acid (Nervonic ac... | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_25:0_pentacosanoic_acid | 8 | serum_lipidomics | FA 25:0 Pentacosanoic acid | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| fa_26:0_cerotic_acid | 8 | serum_lipidomics | FA 26:0 Cerotic acid | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| gsl_d18:1/c12:0 | 8 | serum_lipidomics | GSL d18:1/C12:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| glccer_d18:1/c16:0 | 8 | serum_lipidomics | GlcCer d18:1/C16:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| glccer_d18:1/c22:0 | 8 | serum_lipidomics | GlcCer d18:1/C22:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| glccer_d18:1/c24:1 | 8 | serum_lipidomics | GlcCer d18:1/C24:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| laccer_d18:1/c12:0 | 8 | serum_lipidomics | LacCer d18:1/C12:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| laccer_d18:1/c16:0 | 8 | serum_lipidomics | LacCer d18:1/C16:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| laccer_d18:1/c24:1 | 8 | serum_lipidomics | LacCer d18:1/C24:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysopc_20:4 | 8 | serum_lipidomics | LysoPC 20:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysopc_20:5 | 8 | serum_lipidomics | LysoPC 20:5 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysope_20:4 | 8 | serum_lipidomics | LysoPE 20:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_(p-16:0/0:0) | 8 | serum_lipidomics | PC (P-16:0/0:0) | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_32:1 | 8 | serum_lipidomics | PC 32:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_32:3 | 8 | serum_lipidomics | PC 32:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_34:0 | 8 | serum_lipidomics | PC 34:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_34:1 | 8 | serum_lipidomics | PC 34:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_34:2 | 8 | serum_lipidomics | PC 34:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_34:3 | 8 | serum_lipidomics | PC 34:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_34:4 | 8 | serum_lipidomics | PC 34:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_34:5 | 8 | serum_lipidomics | PC 34:5 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_36:0 | 8 | serum_lipidomics | PC 36:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_36:3 | 8 | serum_lipidomics | PC 36:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_38:1 | 8 | serum_lipidomics | PC 38:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_38:2 | 8 | serum_lipidomics | PC 38:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_38:5 | 8 | serum_lipidomics | PC 38:5 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_38:7 | 8 | serum_lipidomics | PC 38:7 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_40:1 | 8 | serum_lipidomics | PC 40:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_40:2 | 8 | serum_lipidomics | PC 40:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_40:3 | 8 | serum_lipidomics | PC 40:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_40:4 | 8 | serum_lipidomics | PC 40:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_40:5 | 8 | serum_lipidomics | PC 40:5 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_40:6 | 8 | serum_lipidomics | PC 40:6 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_40:8 | 8 | serum_lipidomics | PC 40:8 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_42:2 | 8 | serum_lipidomics | PC 42:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_42:3 | 8 | serum_lipidomics | PC 42:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pc_44:12 | 8 | serum_lipidomics | PC 44:12 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pce_34:0 | 8 | serum_lipidomics | PCE 34:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pce_34:1 | 8 | serum_lipidomics | PCE 34:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pce_38:4 | 8 | serum_lipidomics | PCE 38:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pce_38:5 | 8 | serum_lipidomics | PCE 38:5 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pe_34:2 | 8 | serum_lipidomics | PE 34:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pe_36:1 | 8 | serum_lipidomics | PE 36:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pe_36:2 | 8 | serum_lipidomics | PE 36:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pe_36:3 | 8 | serum_lipidomics | PE 36:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pe_36:4 | 8 | serum_lipidomics | PE 36:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pg_34:0 | 8 | serum_lipidomics | PG 34:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pi_36:4 | 8 | serum_lipidomics | PI 36:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| pi_38:5 | 8 | serum_lipidomics | PI 38:5 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| ps_36:0 | 8 | serum_lipidomics | PS 36:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| ps_36:1 | 8 | serum_lipidomics | PS 36:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| ps_37:2 | 8 | serum_lipidomics | PS 37:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| ps_38:2 | 8 | serum_lipidomics | PS 38:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| ps_38:3 | 8 | serum_lipidomics | PS 38:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| ps_39:1 | 8 | serum_lipidomics | PS 39:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| ps_40:3 | 8 | serum_lipidomics | PS 40:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| ps_40:4 | 8 | serum_lipidomics | PS 40:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| ps_42:4 | 8 | serum_lipidomics | PS 42:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| ps_44:3 | 8 | serum_lipidomics | PS 44:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| ps_44:6 | 8 | serum_lipidomics | PS 44:6 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| ps_44:7 | 8 | serum_lipidomics | PS 44:7 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| sm_d18:1/c12:0 | 8 | serum_lipidomics | SM d18:1/C12:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| sm_d18:1/c18:0 | 8 | serum_lipidomics | SM d18:1/C18:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| sm_d18:1/c18:1 | 8 | serum_lipidomics | SM d18:1/C18:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| sm_d18:1/c20:0 | 8 | serum_lipidomics | SM d18:1/C20:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| sm_d18:1/c24:0 | 8 | serum_lipidomics | SM d18:1/C24:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_40:0 | 8 | serum_lipidomics | TAG 40:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_40:1 | 8 | serum_lipidomics | TAG 40:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_41:0 | 8 | serum_lipidomics | TAG 41:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_42:0 | 8 | serum_lipidomics | TAG 42:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_42:1 | 8 | serum_lipidomics | TAG 42:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_43:1 | 8 | serum_lipidomics | TAG 43:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_44:0 | 8 | serum_lipidomics | TAG 44:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_44:1 | 8 | serum_lipidomics | TAG 44:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_44:2 | 8 | serum_lipidomics | TAG 44:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_44:3 | 8 | serum_lipidomics | TAG 44:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_45:1 | 8 | serum_lipidomics | TAG 45:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_45:2 | 8 | serum_lipidomics | TAG 45:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_46:0 | 8 | serum_lipidomics | TAG 46:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_46:1 | 8 | serum_lipidomics | TAG 46:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_46:2 | 8 | serum_lipidomics | TAG 46:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_46:3 | 8 | serum_lipidomics | TAG 46:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_47:0 | 8 | serum_lipidomics | TAG 47:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_47:1 | 8 | serum_lipidomics | TAG 47:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_47:2 | 8 | serum_lipidomics | TAG 47:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_47:3 | 8 | serum_lipidomics | TAG 47:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_48:0 | 8 | serum_lipidomics | TAG 48:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_48:1 | 8 | serum_lipidomics | TAG 48:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_48:2 | 8 | serum_lipidomics | TAG 48:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_48:3 | 8 | serum_lipidomics | TAG 48:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_49:0 | 8 | serum_lipidomics | TAG 49:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_49:1 | 8 | serum_lipidomics | TAG 49:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_49:2 | 8 | serum_lipidomics | TAG 49:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_49:3 | 8 | serum_lipidomics | TAG 49:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_50:0 | 8 | serum_lipidomics | TAG 50:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_50:5 | 8 | serum_lipidomics | TAG 50:5 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_51:1 | 8 | serum_lipidomics | TAG 51:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_51:2 | 8 | serum_lipidomics | TAG 51:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_51:3 | 8 | serum_lipidomics | TAG 51:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_51:4 | 8 | serum_lipidomics | TAG 51:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_51:6 | 8 | serum_lipidomics | TAG 51:6 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_52:0 | 8 | serum_lipidomics | TAG 52:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_52:4 | 8 | serum_lipidomics | TAG 52:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_52:7 | 8 | serum_lipidomics | TAG 52:7 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_52:8 | 8 | serum_lipidomics | TAG 52:8 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_53:1 | 8 | serum_lipidomics | TAG 53:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_53:3 | 8 | serum_lipidomics | TAG 53:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_53:4 | 8 | serum_lipidomics | TAG 53:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_53:5 | 8 | serum_lipidomics | TAG 53:5 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_54:1 | 8 | serum_lipidomics | TAG 54:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_54:3 | 8 | serum_lipidomics | TAG 54:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_54:7 | 8 | serum_lipidomics | TAG 54:7 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_54:8 | 8 | serum_lipidomics | TAG 54:8 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_54:9 | 8 | serum_lipidomics | TAG 54:9 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_55:8 | 8 | serum_lipidomics | TAG 55:8 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_56:1 | 8 | serum_lipidomics | TAG 56:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_56:10 | 8 | serum_lipidomics | TAG 56:10 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_56:2 | 8 | serum_lipidomics | TAG 56:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_56:3 | 8 | serum_lipidomics | TAG 56:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_56:5 | 8 | serum_lipidomics | TAG 56:5 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_56:8 | 8 | serum_lipidomics | TAG 56:8 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_56:9 | 8 | serum_lipidomics | TAG 56:9 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_57:8 | 8 | serum_lipidomics | TAG 57:8 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_58:1 | 8 | serum_lipidomics | TAG 58:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_58:10 | 8 | serum_lipidomics | TAG 58:10 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_58:11 | 8 | serum_lipidomics | TAG 58:11 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_58:12 | 8 | serum_lipidomics | TAG 58:12 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_58:2 | 8 | serum_lipidomics | TAG 58:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_58:4 | 8 | serum_lipidomics | TAG 58:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_58:5 | 8 | serum_lipidomics | TAG 58:5 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_58:6 | 8 | serum_lipidomics | TAG 58:6 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_58:9 | 8 | serum_lipidomics | TAG 58:9 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_60:10 | 8 | serum_lipidomics | TAG 60:10 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_60:11 | 8 | serum_lipidomics | TAG 60:11 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_60:12 | 8 | serum_lipidomics | TAG 60:12 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_60:13 | 8 | serum_lipidomics | TAG 60:13 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_60:2 | 8 | serum_lipidomics | TAG 60:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_60:3 | 8 | serum_lipidomics | TAG 60:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_60:4 | 8 | serum_lipidomics | TAG 60:4 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_60:5 | 8 | serum_lipidomics | TAG 60:5 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_60:7 | 8 | serum_lipidomics | TAG 60:7 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_60:9 | 8 | serum_lipidomics | TAG 60:9 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_62:13 | 8 | serum_lipidomics | TAG 62:13 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| tag_62:14 | 8 | serum_lipidomics | TAG 62:14 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysopc_14:0 | 8 | serum_lipidomics | lysoPC 14:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysopc_16:0 | 8 | serum_lipidomics | lysoPC 16:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysopc_17:1 | 8 | serum_lipidomics | lysoPC 17:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysopc_18:0 | 8 | serum_lipidomics | lysoPC 18:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysopc_18:1 | 8 | serum_lipidomics | lysoPC 18:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysopc_18:2 | 8 | serum_lipidomics | lysoPC 18:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysopc_18:3 | 8 | serum_lipidomics | lysoPC 18:3 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysopc_20:0 | 8 | serum_lipidomics | lysoPC 20:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysopc_20:1 | 8 | serum_lipidomics | lysoPC 20:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysopc_22:6 | 8 | serum_lipidomics | lysoPC 22:6 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysope_16:0 | 8 | serum_lipidomics | lysoPE 16:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysope_18:0 | 8 | serum_lipidomics | lysoPE 18:0 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysope_18:1 | 8 | serum_lipidomics | lysoPE 18:1 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
| lysope_18:2 | 8 | serum_lipidomics | lysoPE 18:2 | NaN | NaN | NaN | Continuous | NaN | serum_lipidomics/serum_lipidomics.parquet | NaN | NaN | Accruing | Intensity (log10) | Primary | Both sexes | Single | NaN | 2019-02-19 | log1p | float |
Plot histogram and ecdf for 22:6_cholesteryl_ester at baseline visit
from pheno_utils.basic_plots import hist_ecdf_plots
col = "22:6_cholesteryl_ester"
df = pl[[col] + ["age", "sex", "collection_date"]].loc[:,:,"00_00_visit",0,:]
# plot histogram and ecdf
hist_ecdf_plots(df.dropna(subset=[col,"sex", "age"]), col, gender_col="sex")
# stats
display(df[col].describe().to_frame().T)
| count | mean | std | min | 25% | 50% | 75% | max | |
|---|---|---|---|---|---|---|---|---|
| 22:6_cholesteryl_ester | 5711.0 | 0.949672 | 0.340004 | 0.0 | 0.732755 | 0.961281 | 1.164637 | 2.607505 |