Publications

Sex-specific dietary habits and their association with weight change in healthy adults

Nutrition
Anthropometrics
obesity
Segal lab
BMC Medicine
2024
Rein M, Elkan M, Godneva A, Dolev N, Segal E, BMC Medicine
Nov 6, 2024

Phenome-wide associations of human aging uncover sex-specific dynamics

Aging
Segal lab
Pheno.AI
Nature Aging
2024
Reicher L, Bar N, Godneva A, Reisner Y, Zahavi L, Shahaf N, Dhir R, Weinberger A, Segal E, Nature Aging
Nov 5, 2024

 

Identification of gut microbiome features associated with host metabolic health in a large population-based cohort

Microbiome
Segal lab
Pheno.AI
Nature Communications
2024
Keshet A, Segal E, Nature Communications
Oct 29, 2024

From Glucose Patterns to Health Outcomes: A Generalizable Foundation Model for Continuous Glucose Monitor Data Analysis

CGM
SSL
Diabetes
Nutrition
Segal lab
Pheno.AI
arxiv
2024
Lutsker G, Sapir G, Godneva A, Shilo S, Greenfield J, Samocha-Bonet D, Mannor S, Meirom E, Chechik G, Rossman H, Segal E, arxiv
Aug 20, 2024

 

Continuous glucose monitoring and intrapersonal variability in fasting glucose

CGM
Diabetes
Segal lab
Pheno.AI
Nature Medicine
2024
Shilo S, Keshet A, Rossman H, Godneva A, Talmor-Barkan Y, Aviv Y, Segal E, Nature Medicine
Apr 15, 2024

 

COMPRER: A Multimodal Multi-Objective Pretraining Framework for Enhanced Medical Image Representation

SSL
Fundus
Cardiovascular
Pheno.AI
Segal lab
medRxiv
2024
Lutsker G, Rossman H, Godneva N, Segal E, medRxiv
Mar 18, 2024

Pangenomes of human gut microbiota uncover links between genetic diversity and stress response

Microbiome
Stress
Genomics
Segal lab
Cell Host & Microbe
2024
Shoer S, Reicher L, Zhao C, Pollard K, Pilpel Y, Segal E, Cell Host & Microbe
Jan 1, 2024

 

Genome-wide association studies and polygenic risk score phenome-wide association studies across complex phenotypes in the human phenotype project

Genomics
Sleep
Segal lab
Pheno.AI
Med
2024
Levine Z, Kalka I, Kolobkov D, Rossman H, Godneva A, Shilo S, Keshet A, Weissglas-Volkov D, Shor T, Diament A, Talmor-Barkan Y, Aviv Y, Sharon T, Weinberger A, Segal E, Med
Jan 1, 2024

 

A Multimodal Dataset of 21,412 Recorded Nights for Sleep and Respiratory Research

Sleep
Pheno.AI
Segal lab
ML4H (arXiv)
2023
Diament A, Gorodetski M, Jankelow A, Keshet A, Shor T, Weissglas-Volkov D, Rossman H, Segal E, ML4H (arXiv)
Nov 15, 2023

Impact of dietary interventions on pre-diabetic oral and gut microbiome, metabolites and cytokines

Diabetes
Microbiome
Segal lab
Nature Communications
2023
Shoer S, Shilo S, Godneva A, Ben-Yacov O, Rein M, Wolf B, Lotan-Pompan M, Bar N, Weiss E, Houri-Haddad Y, Pilpel Y, Weinberger A, Segal E, Nature Communications
Sep 4, 2023

 

Gut microbiome modulates the effects of a personalised postprandial-targeting (PPT) diet on cardiometabolic markers: a diet intervention in pre-diabetes

Diabetes
Microbiome
Segal lab
Gut
2023
Ben-Yacov O, Godneva A, Rein M, Shilo S, Lotan-Pompan M, Weinberger A, Segal E, Gut
May 3, 2023

Bacterial SNPs in the human gut microbiome associate with host BMI

Microbiome
Anthropometrics
Segal lab
Nature Medicine
2023
Zahavi L, Lavon A, Reicher L, Shoer S, Godneva A, Leviatan S, Rein M, Weissbrod O, Weinberger A, Segal E, Nature Medicine
Jan 1, 2023

CGMap: Characterizing continuous glucose monitor data in thousands of non-diabetic individuals

CGM
Diabetes
Segal lab
Pheno.AI
Cell Metabolism
2023
Keshet A, Shilo S, Godneva A, Talmor-Barkan Y, Aviv Y, Segal E, Rossman H, Cell Metabolism
Jan 1, 2023

 

An expanded reference map of the human gut microbiome reveals hundreds of previously unknown species

Microbiome
Segal lab
Nature Communications
2022
Leviatan S, Shoer S, Rothschild D, Gorodetski M, Segal E, Nature Communications
Jul 5, 2022

 

Prediction of type 2 diabetes mellitus onset using logistic regression-based scorecards

Diabetes
Segal lab
eLife
2022
Edlitz Y, Segal E, eLife
Jun 22, 2022

 

An atlas of robust microbiome associations with phenotypic traits based on large-scale cohorts from two continents

Microbiome
Segal lab
PLoS ONE
2022
Rothschild D, Leviatan S, Hanemann A, Cohen Y, Weissbrod O, Segal E, PLoS ONE
Mar 24, 2022

 

Effects of personalized diets by prediction of glycemic responses on glycemic control and metabolic health in newly diagnosed T2DM: a randomized dietary intervention pilot trial

CGM
Diabetes
Nutrition
Segal lab
BMC Medicine
2022
Rein M, Ben-Yacov O, Godneva A, Shilo S, Zmora N, Kolobkov D, Cohen-Dolev N, Wolf B, Kosower N, Lotan-Pompan M, Weinberger A, Halpern Z, Zelber-Sagi S, Elinav E, Segal E, BMC…
Feb 9, 2022

 

The Gut Microbiome of Adults With Type 1 Diabetes and Its Association With the Host Glycemic Control

Microbiome
Diabetes
Segal lab
Diabetes Care
2022
Shilo S, Godneva A, Rachmiel M, Korem T, Bussi Y, Kolobkov D, Karady T, Bar N, Wolf B, Glantz-Gashai Y, Cohen M, Levin N, Shehadeh N, Gruber N, Levran N, Koren S, Weinberger…
Jan 19, 2022

 

Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease

Cardiovascular
Microbiome
Metabolomics
Segal lab
Nature Medicine
2022
Talmor-Barkan Y, Bar N, Shaul A, Shahaf N, Godneva A, Bussi Y, Lotan-Pompan M, Weinberger A, Shechter A, Chezar-Azerrad C, Arow Z, Hammer Y, Chechi K, Forslund S, Fromentin…
Jan 1, 2022

 

Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance

Microbiome
Nutrition
Segal lab
Cell
2022
Suez J, Cohen Y, Valdés-Mas R, Mor U, Dori-Bachash M, Federici S, Zmora N, Leshem A, Heinemann M, Linevsky R, Zur M, Ben-Zeev Brik R, Bukimer A, Eliyahu-Miller S, Metz A…
Jan 1, 2022

 

BREAst Cancer Personalised NuTrition (BREACPNT): dietary intervention in breast cancer survivors treated with endocrine therapy - a protocol for a randomised clinical trial

CGM
Cancer
Diabetes
Segal lab
BMJ Open
2022
Rein M, Dadiani M, Godneva A, Bakalenik-Gavry M, Morzaev-Sulzbach D, Vachnish Y, Kolobkov D, Lotan-Pompan m, Weinberger A, Segal E, Gal-Yam E, BMJ Open
Jan 1, 2022

 

Prediction of Personal Glycemic Responses to Food for Individuals With Type 1 Diabetes Through Integration of Clinical and Microbial Data

CGM
Diabetes
Nutrition
Segal lab
Diabetes Care
2021
Shilo S, Godneva A, Rachmiel M, Korem T, Kolobkov D, Karady T, Bar N, Wolf B, Glantz-Gashai Y, Cohen M, Zuckerman Levin N, Shehadeh N, Gruber N, Levran N, Koren S…
Oct 19, 2021

 

Personalized Postprandial Glucose Response–Targeting Diet Versus Mediterranean Diet for Glycemic Control in Prediabetes

Diabetes Care
2021
Ben-Yacov O, Godneva A, Rein M, Shilo S, Kolobkov D, Koren N, Cohen Dolev N, Travinsky Shmul T, Wolf B, Kosower N, Sagiv K, Lotan-Pompan M, Zmora N, Weinberger A, Elinav E…
Jul 23, 2021

 

Population-wide diversity and stability of serum antibody epitope repertoires against human microbiota

Microbiome
PhIP-Seq
Nature Medicine
2021
Vogl T, Klompus S, Leviatan S, Kalka I, Weinberger A, Wijmenga C, Fu J, Zhernakova A, Weersma R, Segal E, Nature Medicine
Jul 19, 2021

 

10 K: a large scale prospective longitudinal study in Israel

Segal lab
European Journal of Epidemiology
2021
Shilo S, Bar N, Keshet A, Talmor-Barkan Y, Rossman H, Godneva A, Aviv Y, Edlitz Y, Reicher L, Kolobkov D, Wolf B, Lotan-Pompan M, Levi K, Cohen O, Saranga H, Weinberger A…
May 15, 2021

 

A reference map of potential determinants for the human serum metabolome

Microbiome
Metabolomics
Nature
2020
Bar N, Korem T, Weissbrod O, Zeevi D, Rothschild D, Leviatan S, Kosower N, Lotan-Pompan M, Weinberger A, Le Roy C, Menni C, Visconti A, Falchi M, Spector T, Vestergaard H…
Nov 11, 2020

 

Clinically Accurate Prediction of Glucose Levels in Patients with Type 1 Diabetes

Diabetes Technology and Therapeutics
2020
Amar Y, Shilo S, Oron T, Amar E, Phillip M, Segal E, Diabetes Technology and Therapeutics
Aug 1, 2020

 

Rich data sets could end costly drug discovery

Nature
2020
Segal E, Nature
Jan 29, 2020

Axes of a revolution: challenges and promises of big data in healthcare

Nature Medicine
2020
Shilo S, Rossman H, Segal E, Nature Medicine
Jan 1, 2020

 

Prediction of gestational diabetes based on nationwide electronic health records

Nature Medicine
2020
Artzi N, Shilo S, Hadar E, Rossman H, Barbash-Hazan S, Ben-Haroush A, Balicer R, Feldman B, Wiznitzer A, Segal E, Nature Medicine
Jan 1, 2020

 

Rationale and design of a randomised controlled trial testing the effect of personalised diet in individuals with pre-diabetes or type 2 diabetes mellitus treated with metformin

CGM
Diabetes
T2DM
Segal lab
BMJ Open
2020
Htet T, Godneva A, Liu Z, Chalmers E, Kolobkov D, Snaith J, Richens R, Toth K, Danta M, Hng T, Elinav E, Segal E, Greenfield J, Samocha-Bonet D, BMJ Open
Jan 1, 2020

 

Structural variation in the gut microbiome associates with host health

Microbiome
Segal lab
Nature
2019
Zeevi D, Korem T, Godneva A, Bar N, Kurilshikov A, Lotan-Pompan M, Weinberger A, Fu J, Wijmenga C, Zhernakova A, Segal E, Nature
Mar 27, 2019

 

The pros, cons, and many unknowns of probiotics

Nature Medicine
2019
Suez J, Zmora N, Segal E, Elinav E, Nature Medicine
Jan 1, 2019

 

Environment dominates over host genetics in shaping human gut microbiota

Microbiome
Nutrition
Segal lab
Nature
2018
Rothschild D, Weissbrod O, Barkan E, Kurilshikov A, Korem T, Zeevi D, Costea P, Godneva A, Kalka I, Bar N, Shilo S, Lador D, Vila A, Zmora N, Pevsner-Fischer M, Israeli D…
Feb 28, 2018

 

Host genetics and microbiome associations through the lens of genome wide association studies

Microbiome
Current Opinion in Microbiology
2018
Weissbrod O, Rothschild D, Barkan E, Segal E, Current Opinion in Microbiology
Jan 1, 2018

 

Bread Affects Clinical Parameters and Induces Gut Microbiome-Associated Personal Glycemic Responses

CGM
Microbiome
Diabetes
Nutrition
Segal lab
Cell Metabolism
2017
Korem T, Zeevi D, Zmora N, Weissbrod O, Bar N, Lotan-Pompan M, Avnit-Sagi T, Kosower N, Malka G, Rein M, Suez J, Goldberg B, Weinberger A, Levy A, Elinav E, Segal E, Cell…
Jan 1, 2017

 

Personalized Nutrition by Prediction of Glycemic Responses

CGM
Genomics
Microbiome
Nutrition
Diabetes
Segal lab
Cell
2015
Zeevi D, Korem T, Zmora N, Israeli D, Rothschild D, Weinberger A, Ben-Yacov O, Lador D, Avnit-Sagi T, Lotan-Pompan M, Suez J, Mahdi J, Matot E, Malka G, Kosower N, Rein M…
Jan 1, 2015
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